Cartilage Micro-model 3D Printing Service

As a trusted 3D bioprinting biotech company, CD BioSciences' experienced team of experts can offer you various types of in vitro model building services based on the high-resolution 3Dmicroflu™ technology platform covering all aspects of life science research. Here, the advantages and applications of 3Dmicroflu™ technology platform in the construction of cartilage micro models are demonstrated in the following section.

Overview of cartilage

Cartilage is composed of chondrocytes and intercellular matrix. Compared to normal and hard bone, the matrix within cartilage is gelatinous and has greater toughness. Cartilage is a connective tissue that is primarily supportive and is mainly found around the joints and spine within the body. It is classified as elastic cartilage, hyaline cartilage and fibrocartilage.

• Elastic cartilage is mainly found in the more elastic areas of the body, such as the most common nose, ears, and rib cartilage. These parts are composed of elastic cartilage, which is mainly used to support the elastic cavity in the body.
• Hyaline cartilage is widely distributed in the body and is mainly located in the joint cavities of synovial joints. Its main function is to relieve vibration as well as to reduce friction.
• Fibrocartilage is found mainly between the vertebrae of the spine, such as the intervertebral discs. They tend to be relatively dense in structure , which mainly serves to fix the joint and relieve vibration.

Cartilage is a small part of human skeleton but widely distributed, and it is indispensable for every joint connection. Its important role in weight-bearing and reducing friction between bones is important for the normal conduct of life activities. Once cartilage problems occur, they can lead to related diseases such as arthritis and chondromalacia.

3Dmicroflu™ in the construction of cartilage micro-models

Cartilage is essential for the support and protection of the bones. When cartilage is injured or diseased it can directly affect the body's motor function. Therefore, it is important to study the diseases affected by cartilage as well as artificial cartilage repair by establishing an in vitro cartilage model. Here, CD BioSciences can provide you with a 3D printing technology platform called 3Dmicroflu™, which can be used for the construction of high-resolution cartilage micro-models in vitro. Depending on the flexibility and scalability of 3Dmicroflu™ technology platform, different designs can be implemented to meet the project requirements. In addition, experienced experts from CD BioSciences can participate in your micro model building process to provide you with experience and advice.

Fig. 1. Chondrogenic micro-models constructed by 3Dmicroflu™ technology platform and applications

In terms of cartilage model construction, 3Dmicroflu™ technology platform from CD BioSciences has the following advantages to meet your implementation needs and perhaps further advance your experimental process.

• Compared to general 3D bioprinting, 3Dmicroflu™ is based on microfluidic printing technology, which can provide you with single-cell precision printing that is more suitable for printing cartilage that truly reflects physiological conditions.
• Personalization of cartilage printing can be achieved based on the use of cells from patients with cartilage diseases. Further, personalized drug and cartilage repair customization can also be achieved.
• CD BioSciences' experts can provide you with one-stop consulting and design services from bio-ink selection to cartilage micro-model construction. The experts' years of experience in 3D bioprinting will help you avoid many detours and save time in model building.

If you are interested in 3Dmicroflu™-based cartilage micro models, please feel free to contact us for customization services. All services are available on a 24/7/365 basis.