Metabolic Disease Mechanism Research Based on 3Dmicroflu™
CD BioSciences is a biotechnology company dedicated to promoting the high resolution 3Dmicroflu™ 3D bioprinting technology platform and high quality customised bioinks that can be applied to 3D printing organ and tissue micro-models. 3Dmicroflu™ technology platform can help you construct in vitro models of metabolic diseases that can realistically reflect in vivo physiological features, providing you with services for disease mechanism studies as well as drug screening. CD BioSciences' experts are always looking forward to your inquiries and orders.
Metabolic diseases are mainly caused by problems in metabolic function, including metabolic disorders and metabolic exuberance. They are mainly classified as diseases of protein metabolism, disorders of glucose metabolism, disorders of lipid metabolism, disorders of water-electrolyte metabolism, disorders of inorganic element metabolism and disorders of purine metabolism. The common metabolic diseases are as follows.
Diabetes mellitus is a metabolic disease characterized by hyperglycemia. Hyperglycemia is caused by defective insulin secretion or impaired its biological action. The long-term presence of hyperglycemia leads to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves.
Gout is directly related to hyperuricemia caused by purine metabolism disorders or reduced uric acid excretion, which is a type of metabolic rheumatism. Gout may also cause kidney lesions. In severe cases of gout, joint destruction and renal impairment may occur.
- Vitamin D deficiency disease
Vitamin D deficiency can lead to impaired bone mineralization, mainly in the form of skeletal deformities, slow growth, muscle weakness and low blood calcium. Vitamin D deficiency affects skeletal development and can cause further neurological symptoms.
In vitro modeling of metabolically dysfunctional organs plays an important role in guiding the development of mechanisms of metabolic diseases and related drugs. Here at CD BioSciences, we can provide you with a professional 3D bioprinting technology platform to advance your research process related to metabolic diseases.
3Dmicroflu™ in the process of research on metabolic disease mechanisms
Organ metabolism is an important function of living organisms to maintain normal physiological activity, and abnormalities in metabolic mechanisms can lead to the development of associated metabolic diseases. On the one hand, research on metabolic mechanisms explores the metabolism of nutrients and energy conversion. On the other hand, studies of the metabolic processes of toxic substances in the body are also necessary. The study of metabolic mechanisms is an important part of basic biological research. CD BioSciences offers the 3Dmicroflu™ technology platform for high-resolution 3D organoid micro-models for the study of organ metabolism, related diseases and toxicity testing during drug development.
Fig. 1. 3Dmicroflu™ in the construction of metabolic disease models.
- Metabolic mechanism research
3Dmicroflu™ technology platform enables high-resolution 3D printing of micro-organ models for the study of metabolic mechanisms, simulating in vitro physiological conditions to study the effects of various factors on metabolic mechanisms.
- Metabolic disease model construction
Metabolic diseases occur when there is a build-up or deficiency of metabolic substances such as glycogen, fats and purines. 3Dmicroflu™ technology platform allows you to build models of different types of diseases through 3D printing for metabolism-related disease. mechanisms and drug development.
- Metabolic disease drug screening
The drug toxicity testing process is actually designed to analyse the ability of living organs to metabolise drug toxicity and is an important piece of data for pre-clinical analysis of drugs. 3Dmicroflu™ technology platform enables the testing of different types of hepatotoxicity, such as hepatotoxicity, cardiotoxicity and nephrotoxicity, through the construction of 3D micro-organ models.
If you are interested in our high-resolution 3Dmicroflu™ 3D bioprinting technology platform, please contact us now for professional services. All services are available on a 24/7/365 basis.
For research use only, not intended for any clinical use.
