Organ Metabolic Mechanism Study Based on 3Dmicroflu™

CD BioSciences is a biotechnology company committed to providing high quality and convenient 3D bioprinting services, having a high resolution 3D printing technology platform based on microfluidic systems called 3Dmicroflu™. 3Dmicroflu™ can be applied to the study of metabolic mechanisms in organoids and tissues in vitro. Our experienced team of experts are always on standby for your enquiries and orders.

Metabolism is the ordered series of chemical reactions that occur in living organisms to maintain life. These chemical processes allow organisms to grow and reproduce, maintain their structure and respond to the external environment. Catabolism and anabolism are the two types of metabolism. Catabolism allows for the breakdown of large molecules to obtain energy (e.g. cellular respiration). Anabolism, on the other hand, can use energy to synthesise the various components required by the cell, such as proteins and nucleic acids. When the processes of material and energy exchange are not balanced or maintained at a normal level, the health of the living organism can become problematic. Livers, kidneys and various digestive organs are the most important metabolic organs in the living body.

• Liver is the main metabolic organ of the living organism, the centre of metabolism and energy supply of various substances, and has various functions such as synthesis, storage, decomposition, excretion, detoxification and secretion.
• kidney is mainly responsible for excreting metabolic waste in the body and have the function of maintaining the stability of electrolytes such as sodium, potassium and calcium and acid-base balance in the body.
• The basic physiological functions of the digestive system are the intake, transfer and digestion of food, the absorption of nutrients and the excretion of waste products, which are carried out through the coordinated cooperation of the various organs of the digestive system.

Micro-organ printing services based on 3Dmicroflu™ applied to organ metabolic mechanism research

Organ metabolism is an important function of living organisms to maintain normal physiological activity, and abnormalities in metabolic mechanisms can lead to the development of associated metabolic diseases. On the one hand, research on metabolic mechanisms explores the metabolism of nutrients and energy conversion. On the other hand, studies of the metabolic processes of toxic substances in the body are also necessary. The study of metabolic mechanisms is an important part of basic biological research. CD BioSciences offers the 3Dmicroflu™ technology platform for high-resolution 3D organoid micro-models for the study of organ metabolism, related diseases and toxicity testing during drug development.

Fig.1. 3Dmicroflu™ technology platform for metabolic mechanism research

• Metabolic mechanism research
  3Dmicroflu™ technology platform enables high-resolution 3D printing of micro-organ models for the study of metabolic mechanisms, simulating in vitro physiological conditions to study the effects of various factors on metabolic mechanisms.
• Metabolic disease model construction
  Metabolic diseases occur when there is a build-up or deficiency of metabolic substances such as glycogen, fats and purines. 3Dmicroflu™ technology platform allows you to build models of different types of diseases through 3D printing for metabolism-related disease. mechanisms and drug development.
• Drug toxicity testing
  The drug toxicity testing process is actually designed to analyse the ability of living organs to metabolise drug toxicity and is an important piece of data for pre-clinical analysis of drugs. 3Dmicroflu™ technology platform enables the testing of different types of hepatotoxicity, such as hepatotoxicity, cardiotoxicity and nephrotoxicity, through the construction of 3D micro-organ models.

If you are interested in our high-resolution 3Dmicroflu™ 3D bioprinting technology platform, please contact us now for professional services. All services are available on a 24/7/365 basis.